Wednesday, June 30, 2010

12 new genes linked to type 2 diabetes

Twelve new genes associated with type 2 diabetes have been identified in the largest study yet of the connections between differences in people’s DNA and their risk of diabetes.

The international consortium of scientists, led by Professor Mark McCarthy of the University of Oxford, report their findings in the journal Nature Genetics.

‘The signals we have identified provide important clues to the biological basis of type 2 diabetes,’ says Professor McCarthy of the Wellcome Trust Centre for Human Genetics at Oxford University. ‘The challenge will be to turn these genetic findings into better ways of treating and preventing the condition.’

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Jun 30, 10 • Diabetes News

No link between diabetes drug and rise in heart attacks

A recent study has discarded any link between increase in heart attacks and the intake of the diabetes drug rosiglitazone.

The clinical trial of 2,368 diabetes patients with cardiovascular disease, reported no increased rate of heart attack or death in patients taking rosiglitazone.

In fact, this analysis found a lower combined rate of death, heart attack and stroke associated with patients taking rosiglitazone compared with those who were not taking a thiazolidinedione drug (rosiglitazone or pioglitazone).

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Jun 30, 10 • Diabetes News

Diabetes misunderstood as a disease of the rich

Without a major breakthrough in preventing and treating diabetes, the number of cases in sub-Saharan Africa is projected to double, reaching 24 million by 2030, according to the Brussels-based International Diabetes Federation (IDF).

A recent study, Diabetes in sub-Saharan Africa, led by the University of Yaound? in Cameroon and published in the British medical journal, The Lancet, said inadequate donor attention and national prevention programmes were creating a global ???public health and socioeconomic time bomb???.

Diabetes is caused by inherited genetic factors and lifestyle choices, and manifests when the body does not produce enough insulin, or cannot break down sugar in the blood, according to the World Health Organisation. 

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Jun 30, 10 • Diabetes Support Blog

The prevention of diabetes can be found in a book of healthy food pyramid recipes

From time to time, the importance of a healthy food pyramid diet was associated with the prevention and treatment of diabetes food pyramid. The U.S. Department of Health and Human Services invites us to a healthy food pyramid diet to reduce the risk of diabetes. A diabetic diet is a healthy food pyramid diet and the need for prediabetics diabetics. A cookbook with healthy recipes for diabetics convivial is a must for any person on a food pyramid diet diabetese.

All this is a diabetic, anyway? A healthy food pyramid diet is the focus of diabetics. Diabetic recipes for a cookbook with diabetes driving and health prediabetics in their quest for a healthy food pyramid diet. The Centers for Disease Control and Prevention (CDC) estimates that in 2007, 23.6 million people in the United States have diabetes. This correct ponds 8% of the population. In addition, 5.7 million Meenjoy with diabetes do not even know. Therefore, if after a diabetes diet is important.

If you??re wondering what it looks like a diabetic, it??s a food pyramid for diabetics on the website of the American Diabetes Association. The diabetes food pyramid is easily accessible from the USDA Food Guide Pyramid.

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Jun 30, 10 • Diabetes Support Blog

Tuesday, June 29, 2010

Inhaled Insulin Rivals Conventional Insulin Therapy for Type 2 Diabetes

In patients with type 2 diabetes, inhaled insulin before each meal, plus insulin glargine before bedtime, is just as effective at controlling blood sugar as conventional twice-daily premixed biaspart insulin therapy, according to new research presented here at the American Diabetes Association (ADA) 70th Scientific Sessions and published in the June 26 issue of the Lancet.

The similarity in benefit comes with 2 important advantages ?? less weight gain and less hypoglycemia, said Daniel L. Lorber, MD, director of endocrinology and associate director of the Theresa and Eugene Lang Center for Research and Education at New York Hospital, in Queens.

Oral antidiabetes drugs can provide glycemic control early on in type 2 diabetes, but progressive beta-cell insufficiency can eventually lead to the need for insulin to lower blood sugar levels and achieve glycemic control, Dr. Lorber said. However, the use of insulin is often a delayed strategy because it is associated with weight gain, hypoglycemia, and the need for subcutaneous injections.

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Jun 29, 10 • Diabetes News

Treatments may slow the progression of diabetic retinopathy

Diabetic retinopathy is an eye disease linked to Type 2 diabetes and is a leading cause of vision loss. But, in research released Tuesday, doctors said they have identified two therapies that may slow the progress of the disease.

People with Type 2 diabetes who adhere to intensive blood sugar control, compared with standard blood sugar control, have reduced progression of retinopathy. In addition, patients treated with a combination of a cholesterol-lowering statin and fibrate drugs also had a lower rate of progression compared with patients taking Statins alone. The study also concluded that intensive blood pressure control provided no other benefits compared with standard blood pressure control.

The data come from the ACCORD study, a landmark clinical trial of more than 10,000 adults with Type 2 diabetes who were at high risk of heart attack, stroke or death.

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Jun 29, 10 • Diabetes News

A Sensor Combined with an Insulin Pump Results in Better Blood Sugar Control in All Age Groups with Diabetes

Adding a continuous blood sugar level sensor to an insulin pump helps patients with type 1 diabetes achieve better blood sugar control compared to the common standard of care, multiple daily insulin injections, concludes a study published on-line today in the New England Journal of Medicine.

The paper is entitled, Effectiveness of Sensor-Augmented Insulin-Pump therapy in Type 1 Diabetes.

???Combining the best technologies for insulin delivery and blood sugar monitoring really pays off for diabetes control,??? says Dr. Bruce Perkins, one of the co-authors of the study, endocrinologist at Toronto General Hospital and Assistant Professor at the University of Toronto. ???Being aware of continuous blood sugar trends and having the tools to do something about them can help committed patients of all ages self-manage their diabetes very well.???

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Jun 29, 10 • Diabetes News

Monday, June 28, 2010

Largest diabetes gene search finds 12 new links

An international team of scientists working on the largest study to date to look at DNA and type 2 diabetes say they have found 12 new gene links that offer important clues to how the chronic disease works.

The consortium of researchers from across Europe, the United States and Canada said their findings would not only improve understanding of what lies behind type 2 diabetes, but suggest new biological processes that can be explored as possible targets for new medicines.

“The signals we have identified provide important clues to the biological basis of type 2 diabetes. The challenge will be to turn these genetic findings into better ways of treating and preventing the condition,” said Mark McCarthy of the centre for human genetics at Oxford University, who led the study, published Sunday in the journal Nature Genetics. 

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Jun 28, 10 • Diabetes News

Thursday, June 24, 2010

View each diagnosis of diabetes on its own

At last count, there were close to a dozen genes connected with the development of Type 2 diabetes.

The number grows each year. As more is learned about the genetic reasons why our bodies lose the ability to control sugar levels in the blood, we have a lot of catching up to do in regard to translating this knowledge into better individualized treatment plans in the doctor??s office.

The rate of medical treatment failure for Type 2 diabetes is simply too high. While the diabetic ultimately is responsible for following the treatment plan, the choice of prescribed drug therapy often can be one size fits all. Failure may not always be the patient??s fault, because many of the underlying causes which triggered the diabetes also might affect the response to treatment.

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Jun 24, 10 • Diabetes Support Blog

Diabetes and depression ail Utahns

Diabetics make up a sliver of the population, but they cost insurance companies the most to cover, according to new data released Wednesday.

And the top drug prescribed to insured Utahns is anti-depressants, with depression another disease that is driving up health care costs.

The data is part of the Utah Department of Health??s All-Payer Database, a collection of medical and pharmacy claims from commercial insurance companies. Patients?? names are removed, but replaced by a unique identifier so their care can be tracked.

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Jun 24, 10 • Diabetes News
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